Gall bladder cancer
Gall bladder cancer is a common cancer of biliary system, and is usually diagnosed at advanced stage
Risk factors are
- Large stone in gall bladder
- Porcelain gall bladder (calcification of gall bladder wall)
- Anomalous union of pancreatico-biliary ductal system
- Family history of gall bladder cancer
Symptoms of gall bladder cancer are
- Persistent pain in upper abdomen
- Weight loss
- Loss of appetite
- Diagnosis is suspected on ultrasonography, which may show irregular thickening of gall bladder wall, or may show mass lesion.
- CECT abdomen is the better modality for evaluation of suspected gall bladder cancer patients, and give information regarding the resectibility
- Surgery offers the best chance of cure, however less than 20 % of cases are operable at time of presentation.
- In unresectable patients, diagnosis is conformed by FNA and microscopy, and chemotherapy can be started, which however has only limited role.
- ERCP and stenting can be done in patients with advanced tumors, for palliation of itching, cholangitis
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