Celiac Disease

Celiac diseases is the disease of mucosa of small intestine.
It is characterized by small bowel dysfunction after ingestion of gluten in wheat.
Symptoms of celiac disease are
  • Diarrhea
  • Stunted growth
  • Bloating
  • Anemia
  • Amenorrhea, infertility and impotence
Diagnosis
  • Serological testing
    • IgA anti tissue transglutaminase
    • IgA antiendomysial antibodies
    • Antigliadin antibodies
  • UGI endoscopy and small intestinal biopsy which reveals villous atrophy
Treatment of celiac disease
  • Withdrawal of wheat/oat/barley/rye containing food items from the diet
  • Dietary supplements
  • Steroids may be helpful in severely ill patients with crisis

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