Gastroliver - GLEC
Conditions & Diseases 1 min read127 words

Peptic ulcer disease

Peptic ulcer is the ulceration within the GIT mucosa as a result of excessive secretion of gastric acid.

Peptic ulcer disease

Peptic ulcer is the ulceration within the GIT mucosa as a result of excessive secretion of gastric acid.

Common sites for peptic ulcer disease are stomach and duodenum.

Common causes

  • H pylori infection
  • NSAIDs
  • Hypercalcemia
  • Cirrhosis
  • Renal failure
  • Cigarette smoking
  • Hypersecretory conditions such as gastrinoma
  • Chronic obstructive pulmonary disease

Symptoms

  • Upper abdominal pain after taking meals
  • Pain radiating to the back
  • Bleeding ulcer causes blood in vomiting or black stool
  • Severe abdominal pain in presence of ulcer perforation

Diagnosis

  • Upper GI endoscopy is indicated for peptic ulcers
  • Biopsy to determine presence of H. pylori in the gastric antrum

Treatment

  • Proton Pump Inhibitors (PPI)
  • H pylori eradication
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